Harm Reduction Legal Drugs vs. Illicit Drugs

What is worse? Pharmaceutical drugs or illegal drugs? Let's look at the facts and determine if one is better then the other.

The internet has made information a nearly infinite commodity, yet valuable trusted information is hard to come by. The super highway is full of as much disinformation as it is information. Even if I was to suggest some sort of expertise in the study of pharmaceutical versus illegal substances, you would have a heck of a time getting anyone to believe you unless you did a double check on other references. This has become habit for truth seekers wanting to maintain their reputation for finding valuable information on the highway of disinformation.

This is one reason you might have sought out this factoid, to help yourself check on the facts and information available about pharmaceuticals and illegal drugs. Are illegal substances as dangerous and evil as the white coats and propagandist would have you believe? Are the sweet miracle drugs they give you from the pharmacy, really as pure and good intentioned as we are told they are?

These are questions that are not asked nearly enough, but thanks to the innovation of the internet and true information, it is becoming a regular thing for individuals everywhere to realize that not everything is as it seems.

Let's look at the differences between Pharmaceuticals/legal drugs and illicit drugs/illegal substances.

Properties: (What they are made of)

-You most basic root street drugs are generally directly derived from plant sources and easily broken down without synthetic help, this would make them "organic", or at least mostly "organic. Some refer to these substances as "natural". (Cannabis, Hashish, Salvia, Opium, Heroine, Cocaine, Mushrooms, LSD, etc)

-You're more advanced street drugs are usually derivatives of pharmaceuticals. Some of them are part organic, some are part synthetic. (methamphetamines, ecstacy, speed, crank, ebombs, PCP, pill cocktails, sherm, etc..)

-Most pharmaceuticals are synthetic in nature. This means that there is generally no part of them that was directly derived from a plant source. At one point in time, almost all pharmaceuticals were simply herb concoctions that some were placed into capsules. Now we see that just about 90% of all pharmaceutical drugs are synthetic and completely made by machines, science and laboratories. (natural pharmaceuticals are generally known as "supplements" or vitamins")

Side Effects: (What are common side effects or reactions to them when they are taken.)

-The most common side effects of the most common pharmaceuticals would make your great grandmother blush, some of them are: rash, stroke, heart attack, clotting, seizure, death, anemia, photosensitivity, slurring, sleeplessness, insomnia, twitching, euphoria, confusion, drowsiness, depression, mood swings, anxiety, hemorrhaging, insanity, heart palpations, deafness, blindness, paralysis, constipation, diarrhea, bloody stool, numbness, poisoning, shock, auto-immune disorder, dementia, autism, fever, vomiting, sight disturbances, irregular breathing, hives, liver failure, kidney failure, cancer and more.

-The most common side effects with Organic type illegal drugs:

*Cannabis, Hashish: Euphoria, uncontrollable laughter, momentary excessive cough, drowsiness, hunger, dry mouth, excessive energy, though provocation, paranoia, short term memory loss, burnt fingers, physiological (mental) addiction.

*Opium, Heroine: Physical addiction, lucid dreaming, drowsiness, digestive system mutations, scarring, ticks, scabs, anxiety, aggression, depression, manic depression, stroke, heart attack, kidney failure, AIDS, HIV, Hepatitis, tetanus, cancer, death.

*Cocaine, Coke: Anxiety, excessive energy, heart palpations, sleep disturbances, heart attack, hypersalvation, hyposalvation, dehydration, erectile dysfunction, aggression, sexual dysfunction, stroke, kidney failure, liver failure, death, bronchial infection, sinus cancer, weight loss, tuberculosis, lung cancer, anorexia, physical addiction.

*Mushrooms, Salvia (seers sage), organic LSD, organic MDMA (original ecstacy, cannot be found anymore): Slight hallucinations, sight disturbances, dramatic hallucinations, drowsiness, sleeplessness, lucid dreaming, confusion, aggression, delayed bowel movements, diarrhea, cognitive malfunctions, sexual arousal, heightened senses, tracers, vomiting, dizziness, short term memory loss, delayed reactions.

-Most Common Side Effects with Semi or Fully synthetic illegal substances:

*Amphetamines (speed, meth, crank, crystal, etc..): Excessive energy, overreaction, aggression, sexual dysfunction, anxiety, paranoia, fever, liver failure, kidney failure, heart attack, dehydration, excessive perspiration, dizziness, sleep disturbances, insomnia, anemia, anorexia, malnutrition, alertness, sensitivity, manic depression, physical addiction, depression, exaggerated mood swings, cleptomania, immune deficiency, cancer, ticks, death.

*PCP, Ecstacy, Ebombs, Sherm: Extreme hallucinations, ticks, seizure, uncontrollable mood swings, depression, suicidal thoughts, excessive perspiration, fever, dehydration, sleep disturbances, extreme drowsiness, insomnia, sight disturbances, motor sensory dysfunction, rapid heart palpations, physical and physiological addiction, anxiety, euphoria, delayed reactions, slurred speech, confusion, fear, heart attack, stroke, death.

*Pill Cocktails: Stroke, heart attack, heart palpations, hyposalvation, hypersalvation, liver failure, kidney failure, auto immune disease, tumors, cancer, shock, , clotting, nervousness, anxiety, euphoria, rash, weight gain, weight loss, excessive energy, excessive drowsiness, irregular sleep patterns, hemorrhaging, ulcers, hernia's, manic depression, aggression, cognitive dysfunction, mental chemical imbalances, mood swings, physical and physiological addiction, death.

Cost: (how much do they cost per year, if you were the average consumer buying them)

Pharmaceutical prescriptions:

-Estimated from $100 to $200,000 a year +

Organic Illegal Drugs:

-Estimated from $80 to $100,000 a year +

Semi or Fully Synthetic Illegal Drugs:

-Estimated from $200 to $100,000 a year + (numbers are comparatively low because most users run out of money before these estimations end)

Access: (how hard is it to get these substances)

-Organic substances (cannabis, hashish, cocaine): Easy

-Organic substances (mushrooms, hashish, opium, LSD): Moderately Difficult

-Hard substances (amphetamines, heroine, ecstacy): Moderately Easy

-Hard Substances (PCP, Ebombs): Moderately Difficult

-Moonshine, illegal alcoholic substances: Difficult

-Pill Cocktails, Painkillers, illegal prescription pills: Easy

-Legal Prescription Medications/pills: Moderately Easy

Population Addiction Rate: (How many people are addicted to these substances?)

To make it easy, let's go with America. There are over 304,000,000 people in America (according to a 2009 count)

-Pharmaceuticals (legal and illegal): 23,000,000 American's are hooked on pharmaceuticals

-Cannabis, Hashish, Mushrooms, LSD, Opium: estimated near 100 persons could possibly, maybe be considered physiological addicts.

-Cocaine, Heroin, Amphetamines: More than 10,000,000 American's

Overall, you can already see that addiction rates are considerately lower than the propagandist would have the people believe. Yet and still, the highest rate of addiction accompanied by the highest rate of addicts, is with pharmaceuticals. Painkillers, tranquilizers, psychotics, muscle relaxers, inhibitors, etc.

The rates among addictiveness of most organic drugs is low, some of them have extremely addicting qualities, however, the majority of the population do not abuse these substances bad enough to be medically declared addicted. Many of these drugs are used regularly by both medicinal and recreational users without every becoming addicted. They become routine, such as coffee or soda might.

The rates of addiction with semi-synthetic illegal drugs is higher than organic drugs, but still, the statistics show that while a large majority of individuals have tried them at one point in time, or even had a short term addiction to them, they are no longer using nor addicted to these substances as life goes on. Many of these drugs such as LSD, ebombs, sherm, PCP and other drugs are merely tried through boredom, coercion or in passing recreation. Those that do become addicted don't usually live very long through the addiction, usually due to freak accidents caused by hallucinations.

Fully synthetic street drugs are very addictive, yet they rate of addiction jumps around on these hard substances. This is for many reasons. 1) Most users run out of money and resources and eventually are forced to quiet or become criminals, to which they get arrested and killed. 2) Many quickly die from their addictions due to over dose, lowering the number of "live addicts".3) They get sick or infected for one reason or another.

Pharmaceuticals are very addictive and what's more is that they are regularly prescribed and encouraged by doctors, making it difficult for those whom need help for various reasons, to get away from the addictive drugs. Most of these drugs will not directly kill you, which is part of why the statistics show more addicts amongst pharmaceutical users. Pharmaceuticals tend to kill off a person slowly through body changes, chemical imbalances and the slow breakdown of vital functions. Occasional use of pharmaceuticals varies on the danger or addiction level depending on the pharmaceutical and goes up and off the charts when semi-long or long term use comes into play.

Which are a worse? Pharmaceutical Drugs or Illegal Drugs?

With the facts laid out before you, it really is up to you to interpret them.

While many hard street drugs are certainly worse then a few midols, there are also plenty of pharmaceuticals with side effects and addictive qualities that would make a junkie poop his pants. Let's look at a few pro's and con's to end this factoid appropriately.

Pharmaceuticals:

Pro's:

-They are legally available through doctors or pharmacies

-Some can save your life or make your life much easier

Con's

-Many are highly addictive

-All have potential risk of death or worse

-They can be and usually are expensive

-Some can make you more sick then you were to begin with

-Big Pharma Take Over is supported when you take them or purchase them

-Many have not been efficiently tested for safety before prescribing them to patients

-Many doctors are widely unaware of the full side effects of pharmaceuticals they prescribe

-Children are more widely addicted to their prescriptions than any other drugs or substances

-They can create mental chemical imbalances that can never be reversed or cured

-They can create physical changes, illnesses and diseases that can never be reversed or cured

-Most are inaccessible to the public for private production due to legalities

Illegal Drugs:

Pro's:

-They are cheap and you usually don't have to pay taxes on them

-Accessible nearly anywhere

-Many are safer then legal recreational substances

-Some have more appropriate. safer and natural medicinal uses

-Some can save your life or make your life easier than any other way

-Most can produce their own illegal substances and easily gain materials for such procedures

-Most who try these substances, do not continue long term use or become addicts

-Most side effects are widely known and the information is easy to attain.

Con's:

-They are illegal

-Many illegal substances are highly addictive

-Many can cause death or worse within one application

-Some can cause physical or mental changes that can never be reversed or cured

-Some can create lifestyle changes that are extremely hard to change or reverse

-Most are more easily available on school campuses than anywhere else

When it comes to putting any substance in your body, legal or illegal, there are always risks. Some risk your body, some risk your mind and some risk your life. Many risk things that are worse then death and many are hardly imaginable until you read about them in the media, see them for yourself or experience them for yourself. Even with that in mind, most of it is not worth the risk to the majority of individuals whom have tried either legal or illegal substances.

Make sure to do your research before putting any substances, no matter what they are, into your body. The physical vessel you have is the only one you get in this life and you'll want to consider what you might live through and possible have to live with, after your experiences. Many do not consider these concepts in their "bigger picture" and end up causing irreparable damage to their bodies, minds and spirits.

This doesn't mean that you shouldn't or that you won't try substances that are out there, it is simply a warning that it is wisest to know what you are taking before you take it, so that you may at least understand the consequences when they come.

Be Safe and Good Luck!

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Quadriderm Cream

What is Quadriderm cream used for? Quadriderm ointment or cream is a topical dermatological preparation highly effective in treating many skin disorders. Quadriderm cream or ointment should be stored in a cool place and protected from light and moisture. The validity of Quadriderm ointment or cream is 36 months, and is recorded on the outer packaging, in case of expiration render the product unusable.

Quadriderm cream

Quadriderm cream or ointment contains betamethasone as 17 - valerate (0.05%), gentamicin sulfate (0.1%), Tolnaftate (1%) and clioquinol (1%).

Quadriderm cream or ointment - Tubes with 20 grams.

What is Quadriderm cream used for?

Quadriderm ointment or cream is a topical dermatological preparation highly effective in treating many skin disorders.

Quadriderm cream or ointment should be stored in a cool place and protected from light and moisture.

The validity of Quadriderm ointment or cream is 36 months, and is recorded on the outer packaging, in case of expiration render the product unusable.

Tell your doctor the occurrence of pregnancy during treatment or after its termination. Inform your doctor if you are breastfeeding. Follow the advice of your doctor, always respecting the schedules, doses and duration of treatment. Do not stop treatment without the knowledge of your doctor. Tell your doctor the appearance of unpleasant reactions such as burning, itching, irritation and dry skin. Tell your doctor about any medication you are using before the start or during treatment.

Quadriderm ointment or cream is not suitable for ophthalmic use.

TECHNICAL INFORMATION - Quadriderm

Quadriderm cream or ointment is a topical dermatological preparation highly effective in treating many skin disorders. Quadriderm ensures greater safety of therapeutic success, especially when the causative agent cannot be readily identified.

Because it is a composition of four agents with different pharmacological effects, Quadriderm provides anti-inflammatory, antibacterial and antifungal in the treatment of inflammatory and allergic skin disorders complicated by some types of bacteria or fungi, including Candida.

Quadriderm cream uses

Quadriderm is indicated for topical use in dermatoses caused, complicated or threatened by some types dde bacterial or fungal infection, including candidiasis. It is indicated for the prevention and treatment of infections caused by bacteria or fungi in a variety of eczema and other allergic and inflammatory dermatoses. It has been used successfully to treat acne inguinal, chronic dermatoses of the extremities, erythrasma the external ear otitis, balanoposthitis, herpes zoster, dermatitis, eczema, contact dermatitis, dermatitis microbial follicular dermatitis, dyshidrosis, paronychia (candida) anal pruritus, intertrigo, seborrheic eczema, parakeratosis, pustular acne, impetigo of the scalp, neurodermatitis, angular stomatitis, seborrheic dermatitis, occipital area, photosensitivity dermatitis, lichenified and groin ringworm ringworm infections, like tinea cruris, tinea pedis, and tinea corporis.

CONTRAINDICATIONS - Quadriderm

Quadriderm cream or ointment is contraindicated in patients with a history of hypersensitivity to any of its components. It is also contraindicated in cases of tuberculous lesions of the skin, acute herpes simplex, vaccinia and varicella.

WARNINGS - Quadriderm

any adverse effects reported to the systemic application of corticosteroids, which include adrenal suppression, may also take place with topical corticosteroids, especially in children and newborns.

The absorption of Quadriderm cream or ointment will be larger if wide body surface are treated or if the occlusive method is used. Possible safety measures ought to be taken in advance in these situations or when it is prolonged use of the product, particularly in young children.

Prolonged use of topical antibiotics may occasionally result in growth of non-susceptible organisms. If this occurs, or if irritation, sensitization or super infections are present, treatment with Quadriderm cream or ointment should be discontinued and appropriate therapy should be instituted.

The ferric chloride test for phenylketonuria may yield false positive if clioquinol is present in the urine.

Light stains on clothing may occur due to clioquinol.

Quadriderm cream or ointment is not suitable for ophthalmic use.

LS BL: Antifungal Corticosteroid Cream

LS BL cream seems to be an improved form of Chinese BL - a popular antifungal agent more recognized for its whitening effect. Contrary to this, LS BL has the same content as Chinese BL cream. With the recent research of the author, it has been found out that Chinese BL not only possesses ketoconazole but clobetasole as well. In the Philippines, LS BL cream is a registered form of Chinese BL cream. Interestingly, similar to Chinese BL, LS BL cream can also be bought anywhere. This is a review about LS BL cream and some warnings.

In the Philippines, LS BL cream is imported and distributed by Manxing Enterprise Corporation from Shanghai Baolong Pharmaceutical Co. Ltd in China. LS BL cream is legal as it is registered in the Food and Drug Authority (FDA).  Unfortunately, like the unregistered Chinese BL, there are also counterfeit LS BL creams.

LS BL cream facts

Similar to the Chinese BL cream, LS BL has ketoconazole with the corticosteroid clobetasol. LS BL is a combination of a 10mg/g ketoconazole and a 500mcg/g clobetasol. Like the Chinese BL, LS BL is a 7g cream contained in a maroon jar.

LS BL is a prescription topical preparation indicated for fungal infections including tinea cruris (jock itch), tinea corporis (ringworm), tinea pedis (athlete’s foot) etc. Because it also contains clobetasol, LS BL can be a lot helpful when the itching and inflammation are severe.

More to this, LS BL is cited to be effective for dermatitis like seborrhoeic dermatitis, atopic dermatitis or eczema and psoriasis.

LS BL is applied one to two times daily.

Dangers

LS BL cream is contraindicated to individuals who have allergies to its components. Although, it is only applied over the skin, LS BL cream can also reach the systemic circulation. It should not be used for a long period of time or applied in the large area of the body. LS BL is to be used in precaution in pregnant and breastfeeding mothers.

Infants and children are apt to have LS BL cream into the bloodstream because they have larger skin area to body weight ratio in comparison to the adults. Newborns or premature babies can also absorb high quantities of clobetasole because of the incomplete development of the stratus corneum – the outermost layer of the skin.

With ketoconazole alone, any topical agent with this active constituent is an OTC or over-the-counter product. But, because LS BL cream contains clobetasole it is categorized as a prescription medicine.

Clobetasole is a corticosteroid and as a steroid it can cause cushing syndrome, intracranial hypertension and growth retardation in children.  More to this, prolonged use of a potent topical corticosteroid like clobetasole or a preparation containing this active constituent can cause cataract, diabetes mellitus, glaucoma and tuberculosis.

Whitening effect?

Similar to the Chinese BL, LS BL cream is not indicated for skin lightening or whitening effect. LS BL is primarily indicated for fungal infections.

Image by the author

Recommendations and warnings

As mentioned LS BL cream is more legal than the Chinese BL cream in the Philippines. LS BL cream was registered in the FDA (Food and Drug Authority) Philippines since December 2012 under the DR number DR-XY40466.

However, because LS BL is also popular like the Chinese BL, it is usually imitated. The photo of LS BL cream above was a purchase of the author from a grocery store. Interestingly, the clerk was selling it for its whitening benefits, unmindful that LS BL cream is a prescription drug.

LS BL cream, similar to the Chinese BL has clobetasole. A topical preparation containing corticosteroid should not be used for over two weeks. It is frightening that some women use LS BL cream as a beauty lotion. LS BL like Chinese BL is primarily for fungal infections. As LS BL cream contains clobetasole propionate, an advice from a registered physician is essential.

Finally, since LS BL cream is FDA approved. Consumers should only buy this product in registered drug outlets to avoid a counterfeit or fake LS BL cream.

© Phoenix Montoya @ January 28, 2013

References:

  1. LS BL cream leaflet
  2. Clobetasole leaflet
  3. http://www.fda.gov.ph/database/k.pdf
  4. http://www.mayoclinic.com/health/seborrheic-dermatitis/DS00984/DSECTION=causes

Related article:

Ascof and Solmux: A Comparison of Two Cough Remedies

A comparison between the herbal medicine Ascof and the synthetic cough cure Solmux – two popular cough remedy the Philippines. Is Ascof better than Solmux?

In the Philippines, most cough remedies are considered as OTC or Over-The- Counter medications. Customers usually choose a product based on  drug popularity. The more they see or hear about it from the media, the more they feel secure in purchasing the product for their loved ones or for themselves.

 Ascof and Solmux are two common cough cures. While Ascof is known as a herbal remedy, Solmux as a carbocisteine is also notorious for being in the market for 50 years as a mucoregulator in respiratory diseases  since the 1960s. Both claim efficacy and safety, but which of the two is really better?

Ascof

 

Image by the author

Manufactured by Pascual/ Altermed, Ascof (Lagundi) is from a herbal source. It is indicated for bronchospasm in acute bronchial asthma, chronic bronchitis and other bronco pulmonary disorder.

Contraindication: No known contraindication.

Precaution: Pregnancy and lactation.

Side-effect: Itchiness, nausea and vomiting, tachycardia, diarrhea, drowsiness and body malaise.

Solmux 

Image by the author

Solmux (Carbocisteine) is a derivative of cysteine which is an amino acid. It is manufactured by Westmont/ Unilab Consumer Health and its primary use is to reduce the viscosity of pulmonary secretions in patients. It is for wet productive coughs, to help eliminate phlegm.

Contraindication: Peptic ulcer.

Side-effect: GI disturbance, GI bleeding, headache, skin rash.

Ascof and Solmux comparison

  • Formulation

Ascof and Solmux have different formulations. Ascof is available in 300mg tablet, 600mg caplet and in 300mg syrup drug form. It contains powdered Lagundi leaves (Vitex negundo linne family Verbenaceae). Ascof is for mild to moderate cough usually associated with common colds.

Solmux is available in 500mg capsule and in suspension forms. It has a mucolytic property. It is more beneficial in eliminating excessive mucous in the lungs.

  • Relief

Solmux in its encapsulated form has faster effect than Ascof tablet. Capsule forms of medications have greater dissolution compared to tablets thus they have faster relief. On the other hand, syrup has faster effect than suspension types. This means, Ascof syrup has a much faster effect than Solmux suspension.

  • Safety

Ascof reveals some mild side effects on few patients like itchiness, vomiting etc. These adverse reactions as they claim were reported without prevailing complaint with similar frequency on the placebo control. Solmux’s adverse effect involves gastric upsets. This drug is also used in precaution with old people with severe respiratory insufficiency or asthmatic patients.

Ascof VS Solmux

Considering the formulation, Ascof is more attractive for most consumers because of its herbal origin.  As for relief, liquid forms of medication have faster action and both Solmux and Lagundi have these dosage forms. Although, in terms of solid preparations, Solmux capsule is better than Ascof tablet.

Regarding safety, Ascof has no known contraindications and has mild adverse reactions that are reported rarely. However like most drugs, it is used in precaution with pregnant women and in lactation. Solmux on the other hand, causes stomach upsets, thus strictly contraindicated to people with peptic ulcer. More to this, it is also to be used in precaution with old people with weak lungs or asthmatic patients.

So which is better?

Summing it up, Ascof may have all the advantages over Solmux. But, these drugs possess dissimilar modes of action. Solmux is a mucolytic while Ascof is a simple cough formula with an anti-asthma effect. Ascof won’t be effective enough if the cough will be involving too much phlegm in the lungs. On the contrary, Solmux will not be also suitable for a simple cough with asthma involved.

References:

MIMS online

Dovepress

Wilson and Gisvold’s Textbook of Organic Medicinal and Pharmaceutical Chemistry 9th edition

Chinese BL: Antifungal Cream

BL cream is a Chinese 7g topical drug indicated for fungal infections as ring worm, athletes foot etc. Surprisingly some consumers also use it for acne, for pimples and as an underarm whitening cream?

In the Philippines Chinese BL cream is categorized as a counterfeit drug – not that it is fake or ineffective, but simply it is an imported drug unregistered in the country’s Food and Drug Authority. Naturally, these products are banned in drugstores and other drug outlets. However, a Chinese BL cream can also be bought in cosmetic stores, in market places and in the internet. Its price ranges from 15 pesos to 50 pesos – really cheap compared to other topical antifungal medications.

BL cream products have also proven their efficacy. Compared to the equivalent generic, it can relieve a condition faster. More to this, some consumers also revealed that it is also effective in treating psoriasis, acne, pimples and used as a skin lightening cream.

Image source

What’s in Chinese BL Cream?

BL cream contains ketoconazole – an active constituent which is also found in the brand Nizoral (Janssen), Ketovid (Hovid) and Dezor (Hoe). Ketoconazole is a broad spectrum antifungal agent. While the oral dosage form of ketoconazole is indicated for vaginal yeast diseases, systemic yeasts infections and other infections unresponsive to topical forms; creams are mainly for fungal skin diseases like athlete’s foot, ring worm, jock itch, tinea versicolor etc.

Psoriasis, pimples and acne's link to fungal infections

The precise cause of psoriasis is still unidentified; however medical experts believe that there are factors that contribute to the development of this disease. For one thing, psoriasis is said to be caused by genetic mutations which trigger cells in the immune system to attack the skin. Other factors also include skin injury, infections and some drugs like chloroquine, ace inhibitors, beta blockers, indomethacin and corticosteroids.

Regarding infections, aside from bacterial or viral origin, psoriasis can also result from systemic candidiasis like from an untreated vaginal yeast disease. Systemic fungal infections generally affect the whole body which can trigger psoriasis.

Like psoriasis acne can also be produced by systemic candidiasis.

Pimples on the other hand, are skin lesions usually caused by acne, inflammation of hair follicles and sebaceous glands. With the inflammation of hair follicles, one underlying disease can be folliculitis-a fungal infection in the hair caused by Tinea barbae.

Can ketoconazole cure psoriasis, pimples or acne? Can it be a skin whitening agent?

Psoriasis is a chronic inflammatory skin disease found on scalp, elbows, knees, chest and the lower back. It is similar to seborrhea and eczema in its symptoms of thick or raised skin, red or pink patches, and dry skin with flakes similar to dandruff.

Psoriasis has many types and scalp psoriasis is one of these. Ketoconazole shampoos like Nizoral are used in scalp psoriasis. However, the efficacy of ketoconazole usually focuses on the flakes or dandruff and not on the disease itself. Ketoconazole shampoo, although indicated as an antifungal treatment, can also get rid of dandruff even not of fungal origin.

Other than scalp psoriasis, ketoconazole is not indicated for other types of psoriasis.

As for pimples, ketoconazole may be effective depending if it is of fungal causative like folliculitis. Ketoconazole is not for acne, since acne is a result of excessive sebum production and not from a direct fungal cause.

As cited, psoriasis and acne can be triggered by systemic candidiasis. But with this, systemic yeast infections being the source is treated with an oral antifungal. Psoriasis or acne on the other hand, is cured with other medications.

Finally, ketoconazole reveals no bleaching or lightening property. Therefore, any product of ketoconazole is not for skin whitening.

Important:

As a ketoconazole, BL cream should only be applied once a day. It has been known as teratogenic and can harm a fetus. Although, creams are only for localized effect and not systemically, pregnancy should also be considered. Ketoconazole is not for pregnant and lactating mothers. Care should be provided for young children to avoid hypersensitivity reactions. Ketoconazole may cause skin irritation and burning sensation. Infrequently, individuals may also develop contact dermatitis- a condition characterized by severe itching.

© Phoenix Montoya @ March 24, 2011

References:

http://www.druglib.com/druginfo/ketoconazole/description_pharmacology/

http://www.yeastinfectionadvisor.com/systemicyeastinfections.html

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a605014.html

http://www.wrongdiagnosis.com/p/psoriasis/causes.htm

http://www.sulit.com.ph/index.php/view+classifieds/id/2500583/BL+cream?referralKeywords=chinese+bl+cream

Speaking of Skin Care by Parvesh Handa

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Disflatyl Uses and Side Effects

Disflatyl tablets uses and side effects. Active ingredients- Simethicone. Disflatyl tablets amass the gas bubble formed in the stomach and intestine, helping easier routing of gas. It is prescribed for relief from pressure created by excessive formation of gas bubbles in the stomach and intestine.

Disflatyl tablets uses and side effects

Active ingredients- Simethicone.

Disflatyl tablets amass the gas bubble formed in the stomach and intestine, helping easier routing of gas. It is prescribed for relief from pressure created by excessive formation of gas bubbles in the stomach and intestine.

Disflatyl tablets may be prescribed for ailments not listed above.

Dosage

Adults For functional gastric disorder, postoperative Gas Pains and Flatulence: 40 to 125 Mg of Simethicone to be administered orally after meal and at bedtime.

Adults for Endoscopy: 67 Mg of Simethicone as an oral suspension administered just before Endoscopy.

Disflatyl tablets side effects

Rare cases of side effects associated to Disflatyl tablets have been reported. In case any of these side effects occur, seek for immediate medical help. Symptoms include extreme allergic reaction; skin irritation, hives skin rashes, redness, difficulty in breathing, swelling, and chest pain, chest congestion, swelling of the face, lips tongue or throat.

Common side effects include headache, nausea, vomiting, constipation, diarrhea and abdominal cramps. Consult a doctor if any of these side effects of Disflatyl tablets become persistent and troublesome.

Important information on Disflatyl tablets

• Avoid the medication if you are allergic to Simethicone.

• Use the medication after taking your meal at bedtime or follow the instructions prescribed by your doctor. It is important to maintain your diet prescribed by your doctor along with using the medication for effective results. Consult with your doctor the list of food you need to avoid for controlling the ailments.

• Simethicone may interact with other drugs and cause severe side effects, inform your doctor if you are using any other drug, vitamin supplement or herbal remedies for prevailing ailments.

• Avoid using over the counter medication without consulting with your doctor.

• Consult with your doctor before using Disflatyl tablets in case of pregnancy or breast-feeding.

• Avoid overdose; strictly follow the instruction prescribed to you by your doctor. In case of overdose, seek for immediate medical help.

• Store Disflatyl tablets at room temperature away from direct sunlight, hear and moisture. Keep it safely out of reach of children.

• Disflatyl tablets may cause drowsiness, avoid using it while driving or operating heavy machinery.

Ectrin (Erdosteine)

Ectrin indications/ uses Ectrin (Erdosteine) is indicated for treating severe bronchitis, constant bronchitis as well as its exacerbations. It may as well be used for treating respiratory problems portrayed by uncharacteristic bronchial discharge and damaged mucus transportation.

Ectrin (Erdosteine)

Active ingredient- Erdosteine

Ectrin indications/ uses

Ectrin (Erdosteine) is indicated for treating severe bronchitis, constant bronchitis as well as its exacerbations. It may as well be used for treating respiratory problems portrayed by uncharacteristic bronchial discharge and damaged mucus transportation.

Ectrin (Erdosteine) may as well be used for treating other sickness not listed above.

Dosage and administration

 

 Ectrin Capsule: a capsule 2 to 3 times every day.

Ectrin Suspension: Adults as well as Children over 30 kg: 10 mL of Ectrin Suspension (or 2 tablespoon) two times every day.

Children between 20 to 30 kg: 5 mL of Ectrin Suspension (or a tablespoon) three times every day.

Children between 15 to 19 kg 15-19 kg: 5 5 mL of Ectrin Suspension (or a tablespoon) two times every day.

Direction for Reconstitution: To compose 60 mL suspension: Include 42 mL of water and mix properly till all the powder is evenly mixed.

To compose 100 mL suspension: Include 70 mL of water and mix properly till all the powder is evenly mixed.

Contradictions

  • Recognized allergic reaction to erdosteine or any other active ingredients.
  •  For the reason that of a probable intrusion of erdosteine metabolites with the methionine metabolism, erdosteine is no recommended in subjects experiencing hepatic cirrhosis and insufficiency of the cystathionine synthetase enzyme.
  • Ectrin Suspension: Phenylketonuria, because of existence of aspartame.

Special precautions

  • Influences the capability to Drive or control Machinery.
  • Use with caution during pregnancy and lactation: The efficacy of erdosteine at some stage in human pregnancy has not been recognized and consequently, as with all new medicines, its intake is not suggested. Ectrin is furthermore not suggested during breastfeeding.

Ectrin (Erdosteine) side effects

No GI disorders or systemic adverse reactions owing to Ectrin have been experienced. In case any side effects occur and become problematic consult a doctor.

Drug interactions

No injurious reactions have been monitored with other drugs and Ectrin can consequently be used along with bronchodilators and antibiotics.

General information

 

Ectrin (Erdosteine) is from the group of mucolytics and is administered for taking care of wet cough.

Storage

Keep at a temp. less than 30°C. Don’t expose to direct sunlight.

Zentel Worm Medicine Dosage and Side Effects

Zentel worm Medicine, Zentel dosage , Zentel Side effects. ZENTEL Suspension is a wide-range anthelmintic, which is extremely efficient in fighting a broad variety of intestinal helminths. Albendazole (ZENTEL) is in addition effectual in fighting tissue helminth infectivity, like cutaneous larva migrans.

Zentel worm Medicine dosage and Side effects

Zentel active ingredients- Albendazole from the family of benzimidazole grouping of anthelmintic agents.

Albendazole is a white to off-white, neutral or approximately fragrance-free fine particles, which is virtually insoluble in H20 and somewhat solvent in chloroform, ethyl acetate, acetonitrile and methanol. Its molecular mass of Albendazole is 265.33.

PHARMACOLOGY

ZENTEL Suspension is a wide-range anthelmintic, which is extremely efficient in fighting a broad variety of intestinal helminths.

Albendazole (ZENTEL) is in addition effectual in fighting tissue helminth infectivity, like cutaneous larva migrans.

Zentel suspension treatment has also been administered in the elevated dosage, long term therapy of tissue helminth infectivity which includes cysticercosis and hydatid cysts. The antihelminthic interaction of Zentel suspension is considered to be chiefly intra-intestinal. Nevertheless, at elevated albendazole dosage, adequate is absorbed and changed to the dynamic sulphoxide metabolite, to have a curative consequence in opposition to tissue parasites.

INDICATIONS

Single dosage or diminutive therapies of Zentel 400mg are used in the healing of single or mixed infections of tissue and intestinal parasites, in children above two years as well as adults.

Medical research has established Zentel Suspension to be effectual in the therapy of infectivity resulting from:

• Pinworm or threadworm-scientific name Enterobius vermicularis,

• Roundworm- scientific name Ascaris lumbricoides,

• Ancylostoma duodenale

• Hookwarms- scientific name Necator americanus,

• Whipworm- scientific name Trichuris trichiura,

• Clonorchis sinensis.

• Animal hookworm larvae reasoning cutaneous larva migrans

• Strongyloides stercoralis,

• Opisthorchis viverrini.

ZENTEL 400mg is also used for the healing of Taenia spp and Hymenolepis nana contagions, when other vulnerable helminths genders are nearby. Zentel Therapy should be extensive to three days

Zentel Side effects

The following Zentel Side effects were reported at some stage in medical studies.

It ought to on the other hand be observed that serious casualty has not essentially been recognized for these conditions

Common side effects

Abdominal pain was the most regularly observed in short term use.

Uncommon Side effects

Diarrhea, vomiting, nausea, itchiness, dizziness, allergic reactions or skin redness were observed.

Rare side effects

proteinuria,bone pain, and low RBC counts. Allergic reactions which include urticaria, pruritis, and skin rashes have been observed rarely.

These may not be the complete list of possible Zentel Side effects, for additional information consult a doctor.

Amydramine Syrup

Amydramine syrup is a combination of Na citrate, Diphenhydramine HCl and Menthol and is from the group of aminoalkyl ethers administered as systemic antihistamines.

Amydramine syrup

Active ingredients- Na citrate, Diphenhydramine HCl and Menthol.

Composition/5 mL - Na citrate 28.5 mg, Diphenhydramine HCl 7 mg and menthol 0.55 mg

General information

Amydramine syrup is a combination of Na citrate, Diphenhydramine HCl and Menthol and is from the group of aminoalkyl ethers administered as systemic antihistamines.

Amydramine uses

The medicine is helpful in Relief of cough and easing of nasal as well as bronchial congestion for infants greater than 2 years of age.

 Amydramine syrup may also be administered for other ailments not listed above.

Dosage and administration

Amydramine can be administered with our without meal.

Children greater than or equal to 6 years- Recommended dose 20 mL, can be recurring every 3 hours;

Children between 2 to 5 years 2-5 yr- Recommended dose 20 mL, can be recurring every 3 hours with a maximum limit of 20 mL.

Contraindications

  • Allergic reaction to antihistamines or any of the active components present in Amydramine syrup.
  • Patients with kidney problems or liver disorders.

Special precautions

  • The use of the drug can induce drowsiness; avoid operating heavy machines, driving or executing works which requires high level of mental alertness.
  • To be used with care and caution during pregnancy & lactation.

Amydramine side effects

General

Dizziness, sedation, tinnitus, in coordination, lassitude, fatigue, diplopia, blurred vision, euphoria, insomnia, nervousness and tremors have been associated to the side effects of Amydramine syrup. Avoid administering the drug in case any of these problems become frequent and troublesome.

In case of any symptoms of hypersensitivity, stop using the drug immediately and seek for immediate medical help.

This may not be the complete list of possible Amydramine side effects, consult a doctor for proper knowledge on the subject.

Drug interactions

Sedatives, hypnotics, tranquilizers, aminoglycosides, antimuscarinics, MAOIs and alcohol.

These drugs can react with the active ingredients present in Amydramine syrup causing the possible decline of the subject's situation. The subject ought to be observed for the potential symptoms of the reactivity. Therapeutic intrusion or an alteration in treatment might be necessary.

Alcohol interacts to unstable levels with a wide quantity of therapeutic agents. Avoid consuming alcohol during therapy period.

Grilinctus (Dextromethorphan Hydrobromide), Anti-allergic Cough Medicine

Grilinctus (Dextromethorphan Hydrobromide) Grilinctus (Dextromethorphan Hydrobromide) is a pleasant tasting composition of proved therapeutic agents. It provides symptomatic relief from dry, irritating and allergic cough. Grilinctus (Dextromethorphan Hydrobromide) is a combination; and provides a potent non-narcotic, non-addictive cough suppressant, Grilinctus (Dextromethorphan Hydrobromide) with the anti-allergic effect of Chlorpheniramine Maleate and the soothing properties of Ammonium Chloride and Guaiphenesin.

Grilinctus (Dextromethorphan Hydrobromide)

Grilinctus (Dextromethorphan Hydrobromide) is a pleasant tasting composition of proved therapeutic agents. It provides symptomatic relief from dry, irritating and allergic cough. Grilinctus (Dextromethorphan Hydrobromide) is a combination; and provides a potent non-narcotic, non-addictive cough suppressant, Grilinctus (Dextromethorphan Hydrobromide) with the anti-allergic effect of Chlorpheniramine Maleate and the soothing properties of Ammonium Chloride and Guaiphenesin.

Grilinctus (Dextromethorphan Hydrobromide)a non-narcotic cough suppressant, in contrast to Morphine and Codeine, acts by acting on the cough centre and raises the central threshold for noxious stimuli. While Codeine increases the muscle tone in the intestinal tract thereby tending to reduce peristalsis and cause constipation, Grilinctus (Dextromethorphan Hydrobromide) does not cause constipation or other gastro-intestinal disturbances. Grilinctus (Dextromethorphan Hydrobromide) compares favorably in cough suppressant effectiveness wit Codeine. Being non-toxic and devoid of the undesirable effects of the narcotic cough suppressants, Grilinctus (Dextromethorphan Hydrobromide) is particularly effective in the treatment of spasmodic cough. Because of its wide margin of safety, it is possible to increase the dose of Grilinctus (Dextromethorphan Hydrobromide), in order to obtain a greater cough suppressant effect, for the control of severe paroxysmal coughing.

Ammonium Chloride and Guaiphenesin soothe the mucous lining and relieve irritation in the respiratory tract by direct demulcent effect.

Chlorpheniramine Maleate is one of the most active anti-allergic drugs developed. It is indicated in the treatment of cough occurring as a manifestation of allergy. The incidence of drowsiness after Chlorpheniramine Maleate is minimal as compared to other anti-allergies. It controls nasal congestion and post pharyngeal secretions adding much to the comfort of the patient. Moreover, since Chlorpheniramine Maleate does not have significant anti-cholinergic (atropine like) activity, it does not produce drying of mucosa and hence, it does not interfere with the body's natural process of cough expulsion.

INDICATIONS:

For symptomatic treatment of dry, irritating cough and cough of allergic etiology.

FORMULA:

Each 5 ml of Grilinctus contains :

Dextromethorphan Hydrobromide I.P. 5.0 mg

Chlorpheniramine Maieate I.P. 2.5 mg

Guaiphenesinl.P. 50.0 mg

Ammonium Chloride I.P. 60.0 mg

Syrup, flavorings etc. q.s.

Colours:

Ponceau 4R (Colour Index 16255)

Carmoisine (Colour Index 14720)

Caramel I.P.

DOSAGE:

Adults : 1 teaspoonful (5 ml) of Grilinctus (Dextromethorphan Hydrobromide) three to four times a day. Children : Above 2 years : Proportionately lesser dosage depending upon their age or as prescribed by the Physician.

CAUTION :

It is not advisable to prescribe Grilinctus (Dextromethorphan Hydrobromide) to children below two years. GRILINCTUS should not be taken by engine crews, vehicle drivers, machine operators, etc. Immediately before duty or while on duty.

PRESENTATION :

Grilinctus (Dextromethorphan Hydrobromide) is pleasantly flavored and presented in a 100 ml bottle and a 450 ml bottle.

 

Surfaz SN Anti Fungal, Antibacterial and Anti-inflammatory Cream

Surfaz SN cream offers potent anti fungal action with anti-inflammatory and antibacterial action. INDICATIONS: Surfaz SN cream is used in the management of a range of provocative dermatological problems, along with bacterial or external fungal skin infections.

Surfaz SN Anti fungal, Antibacterial and Anti-inflammatory cream

Active ingredients

• Clotrimazole I P 1.0% w/w

• BeclomethasoneD propionate IP 0.025% w/w

• Neomycin Sulphate I. P. 0.5% w/w

• Cream base. q.s.

• Preservatives.

• Mettiyi Paraben I. P. 0.15% w/w

• Propyl Paraben I. R. 0.08 % w/w

• Appropriate overages added.

Since the precise etiological diagnosis is not always possible to be made only on clinical grounds, in a country like ours, where sophisticated laboratory facilities required for making precise diagnosis are either absent or beyond the reach of the common man, a skin preparation having a broad spectrum of action such as Surfaz SN cream having anti-inflammatory, antibacterial and potent antifungal activities Is very much required.

Many times though when the infection is due to fungus there is a chance of secondary bacterial infections or vice versa. At times the inflammatory skin disorders, which respond to topical corticosteroids, are superadded with bacterial and / or fungal infections of the skin. In these conditions, treatment with anti-inflammatory agents alone is not sufficient and a proper antibiotic has to be added in the regimen.

Justification for individual active ingredients in Surfaz SN Cream

Beclomethasone Dipropionate is one of the potent fluorinated corticosteroids. In the classification of topical steroids based on their potencies, Beclomethasone Dipropionate is classified as a potent steroid, whereas Betamethasone Benzoate as well as Betamethasone Valerate is classified as moderately potent steroids. Like any other topical steroids, it has the following properties:

• Anti-inflammatory action

• antipruritic action

• Vasoconstrictor action

By these 3 actions, Beclomethasone Dipropionate promptly controls symptoms such as itching, swelling, redness and scaling. Studies have proved that Beclomethasone Dipropionate is admirably suited for topical therapy. In fact Beclomethasone Dipropionate was found to possess remarkable local anti-inflammatory activity and low absorption properties which constitute valid justification for its topical use in dermatology. - 0.025% Beclomethasone Dipropionate Cream is an extremely active and effective preparation with low incidence of side reaction.

Clotrimazole is a synthetic imidazole derivative. It is a wide range topical antifungal medication having fungicidal properties against all the fungi liable for apparent fungal skin infections. It has potent action against dermatophytes i.e tinea barbae infections. As tinea infections like Tinea baroae, Tinea capitis, Tinea corporis, Tinea cruris, Tinea manum, Tinea pedis and Tinea unguium are very common in tropical country like India, Clotrimazole has tremendous role to play. Since Clotrimazole also takes care of Pityriasis versicolor and candidal infection it is the right choice of topical antifungal in eradicating tinea infections, candidal Infections and Pityriasis versicolor.

NEOMYCIN SULPHATE is an antibiotic with wide range properties and is very well acceptrd when used topically.

Surfaz SN cream offers potent anti fungal action with anti-inflammatory and antibacterial action.

INDICATIONS:

Surfaz SN cream is used in the management of a range of provocative dermatological problems, along with bacterial or external fungal skin infections.

DOSAGE & ADMINISTRATION:

Surfaz SN cream should be sparingly and uniformly used to the influenced site 2-3 times every day.